Product Overview
Genestra Herbotox Capsules- 90 caps
• Synergistic multi-botanical preparation • Dandelion, Uva-ursi, Cascara sagrada, Beet and Parsley • Ideal for vegans • Convenient capsule format increase patient compliance • Herbotox Capsules provides synergistic herbs such as dandelion, uva-ursi, cascara sagrada and parsley in a convenient capsule format. The capsules are 100% pure vegetable-sourced.
Additional product info: Dandelion root at 1.5-24 g per day is traditionally used in Herbal Medicine to help increase bile flow (cholagogue) and as a diuretic (1). Cascara sagrada bark at 0.25-3 grams per day is traditionally used in Herbal Medicine as a stimulant laxative. Used for the short-term relief of occasional constipation, and to promote bowel movement (2).
Apigenin is a flavone found in vegetables, seasonings and oranges, and it possesses antioxidant activity in vitro. Parsley (Petroselinum crispum) contains large amounts of apigenin, and the low concentration of other flavonoids in this plant makes it suitable for an intervention study with a natural source of apigenin. Seven men and seven women participated in a randomized crossover trial to study the effect of intake of parsley on the urinary excretion of flavones and on biomarkers for oxidative stress. The subjects received a strictly controlled diet low in flavones and other naturally occurring antioxidants during the 2 weeks of intervention. This basic diet was supplemented with parsley providing 3.73–4.49 mg apigenin/MJ in one of the intervention weeks. The parsley intervention resulted in significant increases in the two antioxidant enzymes glutathione reductase (GR) and superoxide dismutase (SOD). Apigenin was detected in all the urine samples collected after parsley intervention (3). The German E-Commission approved the use of parsley at 6 g per day in flushing out the efferent urinary tract in disorders of the same an in prevention and treatment of kidney gravel (4).
References: 1 NHPD Monograph on Dandelion. January 2008. 2 NHPD Monograph on Cascara sagrada. October 2008. 3 Nielsen SE, Young JF, Daneshvar B, Lauridsen ST, Knuthsen P, Sandström B, Dragsted LO. Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects. Br J Nutr. 1999 Jun;81(6):447-55. Yellow highlights 4 Blumenthal, Mark, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin, TX: American Botanical Council, 1998. (Seroyal Research doc)
